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Two HIV-Positive Patients Free of Virus

HIVDoctors have revealed that two patients being treated for lymphoma who underwent chemotherapy and bone marrow transplants involving stem cells have subsequently no trace of HIV.

The cases were presented at the International AIDS Society conference in Kuala Lumpur, Malaysia yesterday. The treatment is not being considered as a cure as the technique is life threatening in itself, but AIDS experts are encouraged by the findings.

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The two patients, who were on long term antiretroviral  therapy when they developed Lymphoma. To treat the cancer the patients were given reduced chemoptherapy and the bone marrow transplant.

The process is similar to the one that Timothy Ray Brown underwent in 2010. Often referred to as ‘The Berlin Patient’, Mr Brown is believed to be the first person to be cured of HIV.

Doctors are not calling this approach a cure though because to implement it,  they would have to weaken a person’s immune system to life threatening levels to deliver the bone marrow transplant. It is only ethically possible with patients who already have developed life threatening conditions.

The discovery was reported by Dr Timothy Henrich of Harvard Medical School and Brigham and Women’s Hospital in Boston. Dr Henrich had been awarded a grant to conduct research in this area from amfAR, the Foundation for AIDS Research. amfAR CEO Kevin Roberts said the findings presented important new information,

“These findings clearly provide important new information that might well alter the current thinking about HIV and gene therapy,” said Frost. “While stem-cell transplantation is not a viable option for people with HIV on a broad scale because of its costs and complexity, these new cases could lead us to new approaches to treating, and ultimately even eradicating, HIV.”

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